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The first appearance of this sense of futility (in the heart's deeper life), may pass disregarded and unheeded. But it will return again and again, and grow apace, until the unsatisfactoriness of a wholly materialistic life, the transitoriness of a merely earthly happiness, achieve recognition and obtain acceptance. With this negative phase, modern man's inner life begins.

-- Notebooks Category 1: Overview of the Quest > Chapter 2 : Its Choice > # 196