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Intense happiness felt on hearing some important good news will start a smile on the face. Intense anxiety wrinkles the forehead and depresses the mouth; if it becomes habitual and chronic, the bowels become constipated. These two facts about wholly opposite moods are known to nearly everyone, because the line of causality is straight, obvious, and universally witnessed. What is less known because harder to discern is the third fact that selfish inconsiderate stubbornness and constant hatred create the poison of uric acid in the bloodstream and this indirectly leads to rheumatism. What is first felt mentally is almost immediately reflected physically.
-- Notebooks Category 10: Healing of the Self > Chapter 3 : The Origins of Illness > # 77