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Atomic science needed mathematical formulae and equations to carry on its work. They are, after all, symbols and abstractions, that is, pure concepts. So too physical science now needs metaphysical concepts to carry its work further. The refusal to do so on the objection that metaphysics is not physics leaves the scientist powerless to answer his own ultimate questions.

-- Notebooks Category 7: The Intellect > Chapter 6 : Science > # 148